In modern mining, papermaking, electricity, and heavy industry, the continuous operation of rotating machinery is directly related to the availability and safety of factories. The Metso DNA machine condition monitoring system, as an integrated online monitoring solution, achieves early warning of mechanical faults such as bearing wear, imbalance, misalignment, and gear meshing problems through fixed installation of vibration sensors, temperature sensors, and process parameter collection. However, any complex automation system will encounter problems such as component aging, signal abnormalities, and configuration failures during long-term operation. This article is aimed at on-site maintenance engineers and condition monitoring experts, systematically reviewing the typical fault phenomena, diagnostic logic, and standard troubleshooting steps of the Metso DNA system (including ACN MR controller, ACN I/O M120, AIF8 analog input unit, RVT/TT-125 dual output sensor, and intelligent alarm processing module) to ensure the high availability of equipment and the reliability of predictive maintenance data.