Product Overview
The National Instruments PCI-6289 is a multifunction data acquisition card for PCI based computers. It belongs to the NI M Series DAQ family and provides 32 analog input channels with 18 bit resolution, four analog output channels, 48 digital input and output lines, and two counters. The card is designed for high channel count measurement in laboratory, industrial, and automated test applications.
The PCI-6289 installs in a standard PCI slot and is supported by NI-DAQmx software. Its high analog input channel count and 18 bit resolution make it useful when many sensors must be monitored with fine measurement detail in one computer. The card can serve as the central measurement interface for a test bench or data logging system.
High Resolution Analog Input
The card provides 32 analog input channels with 18 bit resolution and a maximum single channel sampling rate of 625 kS/s, with the aggregate rate shared across active channels. Selectable input ranges allow the card to be matched to different signal levels, from low voltage sensors to higher level industrial signals. The 18 bit resolution supports detection of small signal changes in the presence of larger offsets.
The analog input system supports hardware timed acquisition, triggering, and multi channel scanning. Engineers can use the card for static monitoring, trend logging, and moderately fast waveform capture. Differential and single ended wiring options help adapt the input configuration to the signal source and noise environment.
Analog Output and Digital I/O
The PCI-6289 includes four analog output channels for control voltages, setpoints, and simple waveforms. These outputs can be used for stimulus generation or for closing a control loop in a test application. Engineers should verify the output range and settling behavior for the connected device.
The card also provides 48 digital input and output lines for logic control, relay driving, and status monitoring. Two 32 bit counters support event counting, frequency measurement, pulse generation, and position sensing. The combination of analog and digital functions allows the card to handle mixed signal tasks in one PCI slot.
Timing and Synchronization
NI-DAQmx provides trigger and clock configuration for the PCI-6289. Start triggers, reference triggers, and sample clocks allow acquisition to be aligned with external events. The card can be synchronized with other DAQ devices where the system architecture supports shared timing and triggering.
For large channel count systems, multiple cards can be used together with appropriate timing distribution. Engineers should document the clock source and trigger routing so that the system can be reproduced. Careful planning of channel mapping and scan order helps avoid confusion when analyzing data from many sensors.
Software and Accessories
The PCI-6289 is supported by NI-DAQmx and can be programmed with LabVIEW, LabWindows/CVI, Measurement Studio, and other NI-DAQmx compatible environments. The driver handles channel configuration, scaling, calibration metadata, and task management. Signal conditioning accessories and shielded cables are available to connect sensors and signals to the card.
Installation requires a PCI slot with adequate airflow and a host computer within the supported specifications. Cables should be routed away from power switching equipment, and shields should be terminated according to the accessory documentation. Regular verification of channel function and calibration supports long term measurement confidence.
Typical Applications
High channel count analog data acquisition
Laboratory monitoring and data logging
Automated test with mixed analog and digital signals
Sensor and transducer measurement
Control voltage generation and stimulus
PCI based test and measurement systems
The PCI-6289 provides 32 analog inputs at 18 bit resolution, 4 analog outputs, 48 digital I/O lines, and 2 counters in an M Series PCI card. Its channel count, resolution, and NI-DAQmx support make it a practical choice for high channel count measurement applications.




