How can national laboratories break down barriers and resistance in the field of life sciences?

Bioisland Laboratory (Guangzhou Regenerative Medicine and Health Guangdong Laboratory) was established in December 2017, is one of the first provincial laboratories in Guangdong Province to cultivate and create a national laboratory "reserve team" as the goal to start construction.

Target direction: Aiming at the cutting-edge research of stem cell and regenerative medicine theory and technology, the layout of regenerative medicine frontier basic research, clinical innovation research, bioinformation, biosafety research and high-end biomedical device consumables research and development of five scientific research directions.

Operation mechanism: To build major science and technology infrastructure and platform, and build regenerative medicine and health frontier research base, clinical application base, achievement transformation and industrialization base and high-level talent base.

The eighth Plenary session of the 11th Sichuan Provincial Committee of the Communist Party of China deployed innovation in the core position of the overall modernization construction, and clarified the goal of scientific and technological innovation development in Sichuan from 2025 to 2035 - in 2025, it will be built into a national innovation-driven development province, and by 2035, it will be basically built into a strong province of science and technology. In order to achieve this goal, Sichuan will strive to become a national laboratory through the construction of Tianfu Laboratory. In February 2021, the "Work Plan for the Establishment of Tianfu Laboratory" was officially issued and implemented.

Layout positioning: higher than the key laboratory of Sichuan Province, heavy quality not weight, in accordance with the "less but fine" layout.

Focus: Focus on life science, space science and technology, advanced nuclear energy, electronic information and other advantages.

In July 2020, Liangzhu Laboratory (Zhejiang Provincial Laboratory of Systematic Medicine and Precision Diagnosis and Treatment) was established, marking the official opening of Zhejiang University Medical Center located in the western Corridor of Science and Technology.

Construction mechanism: Led by Zhejiang University.

Target direction: Guided by disease, focusing on common clinical needs, supported by high-energy technologies such as multi-omics, integrating biotechnology and information technology, and taking clarifying the occurrence and development law of disease phenotype differences as the fundamental scientific task, it focuses on promoting systematic and multi-omics and precise diagnosis and treatment of major psychiatric diseases, difficult undiagnosed diseases, blood and immune diseases and other diseases.

Operation mechanism: Build a high-standard public service platform, and form a full-chain research and development system from cutting-edge science, application basis to clinical trials. Explore a mixed personnel management system.

In July 2020, the West Lake Laboratory (Life Sciences and Biomedicine Zhejiang Laboratory) was officially established.

Construction mechanism: Led by Westlake University, School of Pharmacy, Zhejiang University and Hangzhou Hospital Group jointly participated.

Target direction: Focus on the diagnosis and treatment of metabolic and aging diseases, tumor mechanisms and infectious diseases, and promote translational applied research and emergency medical research through interdisciplinary research methods of multi-field exchanges and cooperation.

Operation mechanism: Three centers are set up: Basic research Center, translational application center and emergency medicine Center. Among them, the basic research Center consists of two clusters of metabolic and aging diseases and tumor mechanism research; The Center for Translational Application consists of two clusters: interdisciplinary research methods and translational application research. The Emergency Medical Center consists of two clusters: microbiology research and vaccine antibody research and development.