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Life Science Ethics: The "two-way Journey" between Science and Life

来源: | 作者:佚名 | 发布时间 :2023-12-07 | 293 次浏览: | Share:

From IVF to assisted reproduction, from embryonic stem cells to human cloning, from synthetic organisms to gene-edited embryos... Every time the field of life science produces breakthrough results and shows great application potential, it will trigger a series of ethical issues based on their different scientific principles and application scenarios.

Recently, the "Opinions on Strengthening the Ethical Governance of Science and Technology" (hereinafter referred to as the "Opinions") has aroused widespread concern in the scientific and technological community. In the view of life science researchers, this document provides a "compass" for the development of cutting-edge scientific ethics rules, and has a milestone significance in the history of life science research.

Peng Yaojin, an associate researcher at the Institute of Zoology of the Chinese Academy of Sciences and a "Zhiyi" researcher at the Beijing Institute of Stem Cell and Regenerative Medicine, said in an interview with reporters: "Facing the future, the Opinions are of great significance to promote ethical legislation of science and technology from a higher level. Of course, this also raises new requirements and challenges for all participants in the existing system."

Experts believe that the ethical governance of life sciences has special significance for both science and people. Its purpose is to better benefit mankind, as if a science and life "two-way".

End Kowloon Water Control

"This is the highest-level and most systematic document to guide the ethical governance of science and technology in the country's history." Peng Yaojin pointed out.

Since 1990's, China began to introduce some laws and regulations in the field of life science, and the contents of ethical governance were included in them. Peng Yaojin said that there are more than 100 normative legal documents related to the field of life sciences. However, the general feeling among researchers is that the norms in some frontier areas of the life sciences "seem to be not yet available."

The ethical governance of researchers runs through the whole process of scientific research, from experimental design, research implementation, result analysis, to the final publication and transformation of results, the entire process should strictly abide by moral conduct and scientific research ethics. However, under the influence of fame, wealth, status and other factors, some researchers have a lax sense of self-discipline, lack or deviation of ethical value judgment, and serious violations of scientific research ethics, which brings challenges to ethical governance.

Experts analyzed that this was because these provisions were scattered in departmental rules and normative legal documents, and did not form a system. At the same time, these documents are at a lower level and only play a role in the department and the system, so the punishment for "foul" behavior is not enough.

For example, the National Health and Health Commission issued the "Ethical Review Measures for Life Science and Medical Research Involving Humans (Draft for Comment)" in 2021, which is mainly aimed at the health system, and has insufficient constraints on enterprises, universities, and research institutes engaged in related work.

In the view of experts, the release of the "Opinions" can not only promote legislation at the national level, but also have the more practical benefit of promoting unified action by various regulatory departments to implement specific systems and truly end the situation of "Kowloon water control".

Science and technology ethics committees face new challenges

The introduction of the Opinions will promote the legislative action of life science ethics across the country, which is also the internal demand for the continuous improvement of China's life science research level.

According to Peng Yaojin, China has made great progress in life science research, such as stem cell and regenerative medicine, synthetic biology and other fields. In some areas, China joins other technologically advanced countries at the forefront of exploration or "no man's land," which is also a "no man's land" for regulatory and ethical governance.

"Therefore, the establishment of a science and technology ethics system in line with China's national conditions and international standards in the frontier field of life sciences is not only an internal demand for the development of life sciences, but also a rare strategic opportunity and condition for China to achieve high-level science and technology self-reliance." Peng Yaojin said.

Facing the future, in the context of consolidating the responsibilities of different innovation entities such as universities, scientific research institutions, medical and health institutions, and enterprises, the science and technology ethics (review) committee under the existing system will face new challenges and requirements.

In recent years, the ethics (review) committee of research institutions in the field of life sciences has been gradually established, but the ability and level of the ethics (review) committee of various institutions are uneven. Peng Yaojin believes that it is necessary to further strengthen the institutional mechanism building and capacity building of the ethics (review) Committee.

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